Group Code: BT2018–2021 Complete Curriculum

Biotechnology Complete Syllabus

Includes mandatory common subjects and core branch subjects for lateral entry.

Engineering Mathematics (Common)

40 Marks
1

Matrices & Determinants

06 Marks
  • Basic concepts of Matrices (Addition, Subtraction and Multiplication), Determinants: Problems on finding unknown quantity in a 2nd and 3rd order determinants using expansion.
  • Solving simultaneous linear equations using determinant method (Cramer’s rule up to 3rd order).
  • Matrices: Minors, Cofactors, Adjoint and Inverse of matrices of 2nd order.
  • Characteristic equation and roots of a square matrix.
2

Vectors

03 Marks
  • Magnitude of a vector.
  • Position vector.
  • Expression of vector in terms of position vectors.
  • Vector in plane and in space in terms of unit vectors i, j and k respectively.
  • Product of vectors.
  • Scalar and vector product.
  • Applications of dot and cross products i.e., Projection of vector on another vector, Area of parallelogram and area of triangle.
  • Work done by a force and moment of force.
3

Probability

01 Marks
  • Random Experiments, Sample Space, Events, Types of Events, Algebra of Events, Complementary event, the events A or B, A and B, A but not B, Mutually Exclusive Events, Exhaustive events, Simple problems.
4

Allied Angles and Compound Angles

06 Marks
  • Signs of Trigonometric ratios, Trigonometric ratios of Allied Angles in terms of θ.
  • Formulae for Sin(A±B), Cos(A±B) & tan(A±B) and problems on them.
  • Multiple and sub multiple angle formulae for 2A & 3A and simple problems.
  • Transformation formulae on sum or difference into products & products into sum or difference and problems on them.
5

Complex Numbers

01 Mark
  • Definition of complex number in the form of a + ib.
  • Conjugate of complex number.
  • Algebra of complex numbers, modulus and principal value of argument of complex number.
  • Polar form Z = r Cosθ + iSinθ.
6

Limits

03 Marks
  • Evaluation of limit of functions by factorization, rationalization, limits when n→∞.
  • Problems on algebraic limits based on formula lim(x→a) (xⁿ − aⁿ)/(x−a) = n·aⁿ⁻¹.
  • Problems on trigonometric limits based on formula lim(θ→0) (sinθ/θ) = 1.
7

Straight Lines

02 Marks
  • Problems on different forms of equations of straight lines such as: y = mx+c, (y-y₁) = m(x-x₁), (y-y₁) = (y₂-y₁)/(x₂-x₁)·(x-x₁).
  • Problems on equation of lines through a point and parallel or perpendicular to a given line.
  • Finding Slope, X-intercept and Y-intercept of general equation ax + by + c = 0.
8

Differentiation Rules

06 Marks
  • Problems on rules of differentiation: (Sum rule, product rule and quotient rule).
  • Problems on function of a function and inverse trigonometric functions.
  • Derivative of implicit functions, and parametric functions and problems.
  • Successive differentiation up to second order and problems on them.
  • Differentiation of Logarithmic functions of types uᵛ, Where u and v are functions of x, Simple problems.
9

Applications

02 Mark
  • Equations of tangent and normal to the curve y = f(x) at a given point and problems.
  • Derivative as a rate measure i.e. to find the rate of change of displacement, velocity, radius, area, volume using differentiation and problems on them.
10

Integration Rules

05 Marks
  • Rules of integration and problems.
  • Problems on integration by the method of substitution and by parts.
11

Definite Integrals

02 Mark
  • Simple problems on definite integrals.
  • Problems on applications of definite integrals such as area and volume.
12

Differential Equations

03 Mark
  • Order and Degree of Differential Equations, Formation of differential equation by eliminating arbitrary constants up to second order.
  • Problems on solution of linear differential equations of first order by variable separable method and integrating factor method.

Applied Science (Common)

40 Marks
1

Unit-I: Mechanics

07 Marks
  • Units: Unit, types of units, SI unit - Basic and Supplementary units, advantages.
  • Measuring instruments: Vernier calipers - principle and least count.
  • Screw gauge - principle, ZE, ZC, pitch and least count.
  • Simple problems on vernier calipers and screw gauge.
  • Scalars and vectors: scalar and vector with example, resultant, equilibrium, equilibrant.
  • Laws of vectors - parallelogram law of vectors, triangle law of vectors, Lami’s theorem.
  • Expression for magnitude and direction of resultant of two vectors acting at a point.
  • Rectangular component of resolution of a vector - simple problems on laws of vectors.
  • Parallel forces: Types of parallel forces, moment of force, couple, moment of couple, simple problems on moment of force.
2

Unit-II: Properties of Solids and Liquids

07 Marks
  • Properties of solids: Deforming force, elasticity and plasticity with examples, stress and its types with example, strain and its types with example, Hooke’s Law, Moduli of elasticity and its types - simple problems on stress and strain.
  • Properties of Liquids: Thrust and pressure, expression for pressure at a point inside the liquid at rest - simple problems.
  • Surface tension: Cohesive and Adhesive forces with examples, surface tension, factors affecting surface tension, application of surface tension.
  • Capillarity and its applications.
  • Viscosity: viscosity, expression for co-efficient of viscosity, effect of temperature on viscosity of liquid and gas, applications of viscosity - simple problems on co-efficient of viscosity.
3

Unit-III: Heat and Properties of Gases

05 Mark
  • Concept of Heat and Temperature: Heat and Temperature, Specific Heat of substance.
  • Transmission of Heat: conduction, convection and radiation with example, Applications of conduction and convection and radiation.
  • Gas laws: Boyle’s law, Charle’s law and Gay-Lussac’s law (statement with expression), expression PV=nRT, Cp and Cv and its relation - simple problems on gas laws.
4

Unit-IV: Wave Motion

08 Marks
  • Simple Harmonic Motion: Periodic motion with example, SHM, expression for displacement of a particle executing SHM.
  • Wave: Wave motion, wave period, wave frequency, wave amplitude, wave length and wave velocity, relation between wave frequency, wave length and wave velocity - problems on V=nλ.
  • Mechanical waves and Non-Mechanical waves with examples, Longitudinal and Transverse waves with example.
  • Propagation of sound waves in air: Newton – Laplace’s formula for velocity of sound in air and various factors affecting velocity of sound in air.
  • Vibrations: Free vibration, forced vibration and resonance with example.
  • Laws of transverse vibration of stretched string, expression for fundamental frequency of vibration of stretched string – simple problems on fundamental frequency.
  • Stationary waves: Stationary waves and its characteristics, beat, beat frequency, application of beats.
5

Unit-V: Modern Physics

05 Mark
  • Electromagnetic waves: Electromagnetic waves and its properties, electromagnetic spectrum and its applications.
  • Laser: Laser, properties of laser and its applications.
  • Nano-technology: Nanotechnology, advantages and dis-advantages of nanotechnology.
  • Communication system: Basic elements of communication system, advantages and dis-advantages of satellite communication system.
  • Optical fibre: Optical fibre - principle and its applications.
6

Unit-VI: Industrial Chemistry

08 Marks
  • Electrolysis: Electrolyte, types of electrolyte with example, electrolysis, Postulates of Arrhenius theory of electrolytic dissociation, Faraday’s First and Second law of electrolysis - simple problems on Faraday’s laws.
  • Corrosion: Corrosion, conditions for corrosion, preventive methods of corrosion.
  • Batteries: Battery, classification and its application.
  • Fuel cells: Fuel cell, types and advantages of fuel cells.
  • Metallurgy: Definition of mineral, ore, flux, slag and alloys.
  • Purpose of making alloys and its applications.
  • Polymers: polymers and its types, application of polymers.
  • Composite materials: Composite material and its types, advantages and dis-advantages of composite material. pH Value: pH value of a solution, pH scale, application of pH in different fields.

Core Branch Subjects (BT)

100 Marks
1

UNIT 1 - CHEMISTRY

5 Marks
  • Atomic structure, Modern periodic table, types of chemical bonds, hybridization and types.
  • Chemical kinetics- Rate studies, order of a reaction, chemical equilibrium, concepts of electrolyte, electrolysis, theories of acids & bases, pH, buffers and catalyst.
  • Organic chemistry: classification and nomenclature.
  • Aliphatic, aromatic hydrocarbons and alcohols - Properties, preparation, uses
2

UNIT 2 - BIOCHEMISTRY

6 Marks
  • Isomerism, Structure, classification and properties of carbohydrates, amino acids peptides, lipids and nucleic acids.
  • Metabolism of carbohydrates and proteins.
  • Bioenergetics - Energy flow cycle, Energy conversion, High energy compounds.
3

UNIT 3 - CELLBIOLOGY

5 Marks
  • Prokaryotes and eukaryotes- Cell structure and organelles, cell cycle, cell division, chromosomes, Mendelian Laws, mutation, karyotype, inherited disorders.
4

UNIT 4 - UNIT OPERATION

5 Marks
  • Unit systems, Sedimentation, Settling, Mixing, Conduction, Convection, radiation, Evaporation, Diffusion, Drying, Absorption, Adsorption & Desorption, properties of fluid, pressure measurements, loss of energy, valves, pumps, Industrial and Production management
5

UNIT 5 - MOLECULAR BIOLOGY & GENETIC ENGINERING

8 Marks
  • Roles of Enzymes in genetic engineering, DNA Replication & Repair, transcription and translation in prokaryotes and eukaryotes.
  • Gene Regulation, recombinant DNA technology, Gene transfer techniques
6

UNIT 6 - BIO-PHYSICAL TECHNIQUES

5 Marks
  • Electrical quantities & units, pH meter, Colorimeters & Spectrophotometers, chromatographic techniques, electrophoretic techniques
7

UNIT 7 - MICROBIOLOGY

7 Marks
  • Microscopy, Bacteria, Fungus, Viruses, Sterilization and Disinfectants, Stains and Staining techniques, Antibiotics, Microbial genetics
8

UNIT 8 - AGRICULTURAL AND ENVIRONMENTAL BIOTECHNOLOGY

7 Marks
  • Interactions among microorganisms & plants, Biological Nitrogen Fixation, Biofertilizers and Biopesticides, Antisense RNA technology, Termination gene technology, Pollution of air, water & soil.
  • Waste water treatment technology, Bioremediation
9

UNIT 9 - IMMUNOLOGY

6 Marks
  • Types of immunity, immune response, antigens, Antibodies, Antigen - Antibody reaction, Vaccines
10

UNIT 10 - FERMENTATION TECHNOLOGY

7 Marks
  • Market Potential of Fermentation Products, Recovery Cost, Design of Fermentor – aseptic operation and containment, body construction, parameters to be monitored and controlled in fermentation process, microbial growth, Reaction kinetics, Control of bioreactor.
  • Antibiotic Fermentation, Anaerobic Fermentation, production of Enzymes, Monoclonal antibodies, Insulin, Erythropoietin, Interferon.
11

UNIT 11 - FOOD AND DAIRY TECHNOLOGY

7 Marks
  • Microbiological analysis milk, Food chemistry, Food spoilage and Food poisoning, Preservation techniques, Production & applications of Yogurt, Cheese, SCP, Probiotics, Neutraceuticals
12

UNIT 12 - BIOPHARMACY

8 Marks
  • Drug of natural origin, pharmaceutical aids, Extraction of drug, pharmacological classification of drugs and its mode of action, Routes of administration of drugs , ADME mechanism, pharmaceutical dosage forms, Quality control, storage and stability of pharmaceutical, biotech and herbal products, Analysis of pharmaceuticals, Manufacturing process of Oral Liquids, Tablets, Capsules, sera and toxoids, Ointments & Injectables
13

UNIT 13 - BIOPROCESS PRINCIPLES AND CALCULATIONS

5 Marks
  • Recommendations for use of units, Concept and problems on Atomic mass, molar mass and Mole, composition of mixtures and Solutions, concentrations, Distillation, Evaporation, absorption, Extraction, Drying, Filtration, Mixing/Blending and Crystallization.
  • Problems on Material Balances involving chemical reactions, heat of reaction, formation and combustion.
14

UNIT 14 - UPSTREAM AND DOWNSTREAM PROCESS TECHNOLOGY

8 Marks
  • Plant Cell, Animal Cell & Microbial Cell culture techniques, Primary Separation Techniques, Product Separation Techniques, Product Recovery
15

UNIT 15 - ENZYMOLOGY

8 Marks
  • Characteristics of enzymes, Classification and nomenclature of enzyme, Concept of holo-enzyme, apo-enzyme, coenzyme & cofactor , Isozymes, Ribozymes, Abzymes, Enzyme specificity , Lock and key, Induced fit theory and Transition state, Isolation of enzymes , Purification of enzymes - Separation based on Solubility, Separation based on molecular size, Separation based on charge, Separation based on specific interaction with other bio molecules, Separation based on Hydrophobic interaction, HPLC, Assay of enzyme activity- Colorimetric, Spectrophotometric, Fluorimetric, Chemiluminescent, Radiometric assays.
  • Immobilization of enzyme.
  • Industrial Applications of Enzymes used in food, dairy, leather, wool industry & in Medical fields, Biosensors.
16

UNIT 16 - BIOINFORMATICS

3 Marks
  • Bioinformatics Definition & concept, Sequence retrieval from Nucleotide databases Sequence retrieval from Protein databases, FASTA, BLAST, Sequence alignment: Single sequence alignments, multiple sequence alignments, Restriction analysis using tool Protein Interaction studies & Visualization of 3D Structure of Protein – Rasmol.